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Cat. No. | Product Name | Target | Signaling Pathways |
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T23557 |
Talibegron hydrochloride
ZD2079 hydrochloride,ZD 2079 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Talibegron hydrochloride (ZD2079 hydrochloride) 是一种β3肾上腺素能受体激动剂,对苯肾上腺素预收缩大鼠肠系膜动脉的 pD2为3.72。松弛大鼠肠系膜动脉和离体主动脉。在体内抑制瘦小鼠 ob 基因表达和循环瘦素水平。 | |||
TP2020 |
[Pro3]-GIP (Mouse)
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GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insul | |||
T83696 |
Gastric Inhibitory Peptide 1 (3-42) (human) TFA
Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42) |
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胃抑制肽1(GIP-1) (3-42)是肠促胰岛素激素GIP的一个肽段,同时也是GIP受体的拮抗剂。它通过血清二肽基肽酶4(DDP-4)从GIP中形成。GIP-1 (3-42) (100 nM)在减少BRIN-BD11胰腺细胞的胰岛素分泌方面起作用。在以25 nmol/kg剂量给药的ob/ob糖尿病小鼠模型中,它能增加血浆葡萄糖水平并降低血浆胰岛素水平。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01725 |
Leptin Receptor Protein, Human, Recombinant (His)
LEPRD,OB-R,OBR,LEP-R,CD295,leptin rece... |
Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight) and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Leptin Receptor/CD295 is transmembrane catalytic receptors found on NPY/AgRP and alpha-MSH/CART ne... | |||
TMPJ-00975 |
LEPR Protein, Mouse, Recombinant (hFc)
CD295,DB,HuB219,OB receptor,LEP-R,Leptin <... |
Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS... | |||
TMPJ-00977 |
LEPR Protein, Mouse, Recombinant (mFc)
LEPR,CD295,OB-R,LEP-R,HuB219,Leptin receptor |
Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS... | |||
TMPJ-00411 |
LEPR Protein, Human, Recombinant (hFc)
LEPR,Leptin receptor,OB-R,OB ... |
Human | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS... | |||
TMPJ-00976 |
LEPR Protein, Mouse, Recombinant (His)
OBR,DB,Leptin receptor,OB rec... |
Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. The human Leptin R gene encodes 1165 amino acids (aa) including a signal peptide, an extracellular region with cytokine receptor homology (CRH), multiple fibronectin type III domains and a WS... | |||
TMPY-00874 |
Leptin Receptor Protein, Human, Recombinant (His & hFc)
LEP-R,OBR,CD295,OB-R,LEPRD,leptin rece... |
Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight) and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Leptin Receptor/CD295 is transmembrane catalytic receptors found on NPY/AgRP and alpha-MSH/CART ne... |